| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CERS5 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CERS5 |
| Gene ID: |
91012 |
| Uniprot ID: |
CERS5_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CERS5 (NP_001268660.1). |
| Immunogen Sequence: |
MMKPRPKRFIAKPCALCIGI EDSGPYQAQPNAILEKVFIS ITKYPDKKRLEGLSKQLDWN VRKIQCWFRHRRNQDKPPTL TKFCESMWRFTFYLCIFCYG |
| Post Translational Modifications | Phosphorylated at the C-terminus by CK2. |
| Function | Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA.C16:0-CoA). Can use other acyl donors, but with less efficiency. N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively. Plays a role in de novo ceramide synthesis and surfactant homeostasis in pulmonary epithelia. |
| Protein Name | Ceramide Synthase 5Cers5Lag1 Longevity Assurance Homolog 5Sphingoid Base N-Palmitoyltransferase Cers5Sphingosine N-Acyltransferase Cers5 |
| Database Links | Reactome: R-HSA-1660661 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ceramide Synthase 5 antibodyAnti-Cers5 antibodyAnti-Lag1 Longevity Assurance Homolog 5 antibodyAnti-Sphingoid Base N-Palmitoyltransferase Cers5 antibodyAnti-Sphingosine N-Acyltransferase Cers5 antibodyAnti-CERS5 antibodyAnti-LASS5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
