| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Pig/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CENTA1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 45kDa band observed in Human Brain (Cerebellum) , Mouse, Rat and Pig Brain lysates (calculated MW of 43.4kDa according to Human NP_006860.1, Mouse NP_766311.2, Rat NP_598251.1 a |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ADAP1 |
| Gene ID: | 11033 |
| Uniprot ID: | ADAP1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_006860.1 |
| Immunogen Sequence: | QEYAVEAHFKHKP |
| Post Translational Modifications | Phosphorylated by PRKCA, PRKCI, PRKCZ and PRKD1 in vitro. |
| Function | GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). |
| Protein Name | Arf-Gap With Dual Ph Domain-Containing Protein 1Centaurin-Alpha-1Cnt-A1Putative Mapk-Activating Protein Pm25 |
| Database Links | Reactome: R-HSA-1251985 |
| Cellular Localisation | NucleusCytoplasmRecruited To The Plasma Membrane Upon Epidermal Growth Factor-Dependent Activation Of Phosphatidylinositol 45-Diphosphate (Ptdinsp2) 3-Kinase |
| Alternative Antibody Names | Anti-Arf-Gap With Dual Ph Domain-Containing Protein 1 antibodyAnti-Centaurin-Alpha-1 antibodyAnti-Cnt-A1 antibodyAnti-Putative Mapk-Activating Protein Pm25 antibodyAnti-ADAP1 antibodyAnti-CENTA1 antibody |
Information sourced from Uniprot.org