Function | RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. |
Protein Name | Cugbp Elav-Like Family Member 3Celf-3Bruno-Like Protein 1Cag Repeat Protein 4Cug-Bp- And Etr-3-Like Factor 3Elav-Type Rna-Binding Protein 1Etr-1Expanded Repeat Domain Protein Cag/Ctg 4Rna-Binding Protein Brunol-1Trinucleotide Repeat-Containing Gene 4 Protein |
Cellular Localisation | NucleusCytoplasm |
Alternative Antibody Names | Anti-Cugbp Elav-Like Family Member 3 antibodyAnti-Celf-3 antibodyAnti-Bruno-Like Protein 1 antibodyAnti-Cag Repeat Protein 4 antibodyAnti-Cug-Bp- And Etr-3-Like Factor 3 antibodyAnti-Elav-Type Rna-Binding Protein 1 antibodyAnti-Etr-1 antibodyAnti-Expanded Repeat Domain Protein Cag/Ctg 4 antibodyAnti-Rna-Binding Protein Brunol-1 antibodyAnti-Trinucleotide Repeat-Containing Gene 4 Protein antibodyAnti-CELF3 antibodyAnti-BRUNOL1 antibodyAnti-CAGH4 antibodyAnti-ERDA4 antibodyAnti-TNRC4 antibody |
Information sourced from Uniprot.org