| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CDS1 (1-80) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CDS1 |
| Gene ID: |
1040 |
| Uniprot ID: |
CDS1_HUMAN |
| Immunogen Region: |
1-80 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human CDS1 (NP_001254.2). |
| Immunogen Sequence: |
MLELRHRGSCPGPREAVSPP HREGEAAGGDHETESTSDKE TDIDDRYGDLDSRTDSDIPE IPPSSDRTPEILKKALSGLS |
| Tissue Specificity | Expressed in adult tissues such as placenta, brain, small intestine, ovary, testis and prostate. Highly expressed in fetal kidney, lung and brain. Lower level in fetal liver. |
| Function | Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol. Exhibits almost no acyl chain preference for PA, showing no discrimination for the sn-1/sn-2 acyl chain composition of PAs. Plays an important role in regulating the growth of lipid droplets which are storage organelles at the center of lipid and energy homeostasis. Positively regulates the differentiation and development of adipocytes. |
| Protein Name | Phosphatidate Cytidylyltransferase 1Cdp-Dag Synthase 1Cdp-Dg Synthase 1Cdp-Diacylglycerol Synthase 1Cds 1Cdp-Diglyceride Pyrophosphorylase 1Cdp-Diglyceride Synthase 1Ctp -Phosphatidate Cytidylyltransferase 1 |
| Database Links | Reactome: R-HSA-1483226 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Phosphatidate Cytidylyltransferase 1 antibodyAnti-Cdp-Dag Synthase 1 antibodyAnti-Cdp-Dg Synthase 1 antibodyAnti-Cdp-Diacylglycerol Synthase 1 antibodyAnti-Cds 1 antibodyAnti-Cdp-Diglyceride Pyrophosphorylase 1 antibodyAnti-Cdp-Diglyceride Synthase 1 antibodyAnti-Ctp -Phosphatidate Cytidylyltransferase 1 antibodyAnti-CDS1 antibodyAnti-CDS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
