Host: | Rabbit |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-CD56 is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | MRQ-42 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
Dilution Range: | IHC 1:100 – 1:500 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Background | CD56, also known as neural cell adhesion molecule (NCAM) , is a calcium-independent homophilic binding protein that belongs to a group of cell adhesion molecules including cadherins, selectins, and integrins. CD56 is involved in cell–cell adhesion of neural cells during embryogenesis and is expressed on most neuroectodermally derived tissues.1-3 In normal tissue, anti-CD56 labels neurons, glia, schwann cells, NK (natural killer) cells, and a subset of T-cells.3 CD56 expression can be seen in most NK cell neoplasms, certain subtypes of T-cell lymphoma and in some plasma cell neoplasms. |
Information sourced from Uniprot.org