Host: |
Alpaca |
Applications: |
ELISA/SPR |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : |
Alpaca monoclonal nanobody anti-Tumor Necrosis Factor Receptor Superfamily Member 5 is suitable for use in ELISA and SPR research applications. |
Clonality : |
Monoclonal |
Clone ID : |
SAA1164 |
Conjugation: |
Unconjugated |
Isotype: |
VHH-8His-Cys-tag |
Formulation: |
0.01M PBS, pH 7.4. |
Purification: |
Purified by Nickel column. |
Concentration: |
1 mg/mL |
Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5B-Cell Surface Antigen Cd40Bp50Cd40l ReceptorCdw40Cd Antigen Cd40 |
Database Links | Reactome: R-HSA-198933 P25942-1Reactome: R-HSA-5668541 P25942-1Reactome: R-HSA-5676594 P25942-1 |
Cellular Localisation | Isoform I: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Ii: Secreted |
Alternative Nanobody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 5 nanobodyAnti-B-Cell Surface Antigen Cd40 nanobodyAnti-Bp50 nanobodyAnti-Cd40l Receptor nanobodyAnti-Cdw40 nanobodyAnti-Cd Antigen Cd40 nanobodyAnti-CD40 nanobodyAnti-TNFRSF5 nanobody |
Information sourced from Uniprot.org