| Post Translational Modifications | Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability. |
| Function | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
| Protein Name | Epithelial Cell Adhesion MoleculeEp-CamAdenocarcinoma-Associated AntigenCell Surface Glycoprotein Trop-1Epithelial Cell Surface AntigenEpithelial GlycoproteinEgpEpithelial Glycoprotein 314Egp314Hegp314Ks 1/4 AntigenKsaMajor Gastrointestinal Tumor-Associated Protein Ga733-2Tumor-Associated Calcium Signal Transducer 1Cd Antigen Cd326 |
| Database Links | Reactome: R-HSA-202733 |
| Cellular Localisation | Lateral Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionColocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction |
| Alternative Nanobody Names | Anti-Epithelial Cell Adhesion Molecule nanobodyAnti-Ep-Cam nanobodyAnti-Adenocarcinoma-Associated Antigen nanobodyAnti-Cell Surface Glycoprotein Trop-1 nanobodyAnti-Epithelial Cell Surface Antigen nanobodyAnti-Epithelial Glycoprotein nanobodyAnti-Egp nanobodyAnti-Epithelial Glycoprotein 314 nanobodyAnti-Egp314 nanobodyAnti-Hegp314 nanobodyAnti-Ks 1/4 Antigen nanobodyAnti-Ksa nanobodyAnti-Major Gastrointestinal Tumor-Associated Protein Ga733-2 nanobodyAnti-Tumor-Associated Calcium Signal Transducer 1 nanobodyAnti-Cd Antigen Cd326 nanobodyAnti-EPCAM nanobodyAnti-GA733-2 nanobodyAnti-M1S2 nanobodyAnti-M4S1 nanobodyAnti-MIC18 nanobodyAnti-TACSTD1 nanobodyAnti-TROP1 nanobody |
Information sourced from Uniprot.org
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