| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
CCNO |
| Gene ID: |
10309 |
| Uniprot ID: |
CCNO_HUMAN |
| Immunogen Region: |
50-150 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CCNO (NP_066970.3). |
| Immunogen Sequence: |
PLPGDSGICDLFESPSSGSD GAESPSAARGGSPLPGPAQP VAQLDLQTFRDYGQSCYAFR KAQESHFHPREALARQPQVT AESRCKLLSWLIPVHRQFGL S |
| Tissue Specificity | Present in respiratory cells (at protein level). |
| Function | Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking. |
| Protein Name | Cyclin-O |
| Cellular Localisation | CytoplasmNucleusNucleolusLocalizes To The Apical Part Of Cytoplasm |
| Alternative Antibody Names | Anti-Cyclin-O antibodyAnti-CCNO antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
