| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CACNB4 |
| Gene ID: | 785 |
| Uniprot ID: | CACB4_HUMAN |
| Immunogen Region: | 401-520 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 401-520 of human CACNB4 (NP_000717.2). |
| Immunogen Sequence: | ATHTTSSTPMTPLLGRNLGS TALSPYPTAISGLQSQRMRH SNHSTENSPIERRSLMTSDE NYHNERARKSRNRLSSSSQH SRDHYPLVEEDYPDSYQDTY KPHRNRGSPGGYSHDSRHRL |
| Tissue Specificity | Expressed predominantly in the cerebellum and kidney. |
| Function | The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. |
| Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Beta-4Cab4Calcium Channel Voltage-Dependent Subunit Beta 4 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-419037 |
| Alternative Antibody Names | Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-4 antibodyAnti-Cab4 antibodyAnti-Calcium Channel Voltage-Dependent Subunit Beta 4 antibodyAnti-CACNB4 antibodyAnti-CACNLB4 antibody |
Information sourced from Uniprot.org