Western blot analysis of extracts of various cell lines, using C1GALT1C1 antibody (STJ29727) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-C1GALT1C1 antibody (30-190) (STJ29727)

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STJ29727
£112.50 - £524.50
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C1GALT1C1
Gene ID: 29071
Uniprot ID: C1GLC_HUMAN
Immunogen Region: 30-190
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 30-190 of human C1GALT1C1 (NP_689905.1).
Immunogen Sequence: IGHGNRMHHHEHHHLQAPNK EDILKISEDERMELSKSFRV YCIILVKPKDVSLWAAVKET WTKHCDKAEFFSSENVKVFE SINMDTNDMWLMMRKAYKYA FDKYRDQYNWFFLARPTTFA IIENLKYFLLKKDPSQPFYL GHTIKSGDLEYVGMEGGIVL S
Tissue Specificity Ubiquitously expressed. Abundantly expressed in salivary gland, stomach, small intestine, kidney, and testis and at intermediate levels in whole brain, cerebellum, spinal cord, thymus, spleen, trachea, lung, pancreas, ovary, and uterus.
Function Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1).
Protein Name C1galt1-Specific Chaperone 1
C38h2-Like Protein 1
C38h2-L1
Core 1 Beta1 -3-Galactosyltransferase 2
C1gal-T2
C1galt2
Core 1 Beta3-Gal-T2
Core 1 Beta3-Galactosyltransferase-Specific Molecular Chaperone
Database Links Reactome: R-HSA-5083632
Reactome: R-HSA-913709
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-C1galt1-Specific Chaperone 1 antibody
Anti-C38h2-Like Protein 1 antibody
Anti-C38h2-L1 antibody
Anti-Core 1 Beta1 -3-Galactosyltransferase 2 antibody
Anti-C1gal-T2 antibody
Anti-C1galt2 antibody
Anti-Core 1 Beta3-Gal-T2 antibody
Anti-Core 1 Beta3-Galactosyltransferase-Specific Molecular Chaperone antibody
Anti-C1GALT1C1 antibody
Anti-COSMC antibody
Anti-HSPC067 antibody
Anti-MSTP143 antibody
Anti-UNQ273 antibody
Anti-PRO310 antibody

Information sourced from Uniprot.org

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