| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BTN1A1 |
| Gene ID: | 696 |
| Uniprot ID: | BT1A1_HUMAN |
| Immunogen Region: | 27-210 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-210 of human BTN1A1 (NP_001723.2). |
| Immunogen Sequence: | APFDVIGPPEPILAVVGEDA ELPCRLSPNASAEHLELRWF RKKVSPAVLVHRDGREQEAE QMPEYRGRATLVQDGIAKGR VALRIRGVRVSDDGEYTCFF REDGSYEEALVHLKVAALGS DPHISMQVQENGEICLECTS VGWYPEPQVQWRTSKGEKFP STSESRNPDEEGLFTVAASV IIRD |
| Post Translational Modifications | N-glycosylated. |
| Function | May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. |
| Protein Name | Butyrophilin Subfamily 1 Member A1Bt |
| Database Links | Reactome: R-HSA-8851680 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecreted |
| Alternative Antibody Names | Anti-Butyrophilin Subfamily 1 Member A1 antibodyAnti-Bt antibodyAnti-BTN1A1 antibodyAnti-BTN antibody |
Information sourced from Uniprot.org