• Western blot analysis of extracts of various cell lines, using BTN1A1 antibody (STJ112146) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-BTN1A1 antibody (27-210) (STJ112146)

SKU:
STJ112146

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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BTN1A1 (27-210) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BTN1A1
Gene ID: 696
Uniprot ID: BT1A1_HUMAN
Immunogen Region: 27-210
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 27-210 of human BTN1A1 (NP_001723.2).
Immunogen Sequence: APFDVIGPPEPILAVVGEDA ELPCRLSPNASAEHLELRWF RKKVSPAVLVHRDGREQEAE QMPEYRGRATLVQDGIAKGR VALRIRGVRVSDDGEYTCFF REDGSYEEALVHLKVAALGS DPHISMQVQENGEICLECTS VGWYPEPQVQWRTSKGEKFP STSESRNPDEEGLFTVAASV IIRD
Post Translational Modifications N-glycosylated.
Function May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Protein Name Butyrophilin Subfamily 1 Member A1
Bt
Database Links Reactome: R-HSA-8851680
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Secreted
Alternative Antibody Names Anti-Butyrophilin Subfamily 1 Member A1 antibody
Anti-Bt antibody
Anti-BTN1A1 antibody
Anti-BTN antibody

Information sourced from Uniprot.org

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