• Western blot analysis of extracts of mouse kidney, using BLVRA antibody (STJ116213) at 1:1000 dilution. _Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. _Lysates/proteins: 25 Mu g per lane. _Blocking buffer: 3% nonfat dry milk in TBST. _Detection: ECL Enhanced Kit. _Exposure time: 90s.

Anti-BLVRA antibody (1-296) (STJ116213)

SKU:
STJ116213

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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BLVRA (1-296) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BLVRA
Gene ID: 644
Uniprot ID: BIEA_HUMAN
Immunogen Region: 1-296
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human BLVRA (NP_001240752.1).
Immunogen Sequence: MNAEPERKFGVVVVGVGRAG SVRMRDLRNPHPSSAFLNLI GFVSRRELGSIDGVQQISLE DALSSQEVEVAYICSESSSH EDYIRQFLNAGKHVLVEYPM TLSLAAAQELWELAEQKGKV LHEEHVELLMEEFAFLKKEV VGKDLLKGSLLFTAGPLEEE RFGFPAFSGISRLTWLVSLF GELSLVSATLEERKEDQYMK MTVCLETEKKSPLSWIEEKG PGLKRNRYLSFHFKSGSLE
Tissue Specificity Liver.
Function Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. Uses the reactants NADH or NADPH depending on the pH.NADH is used at the acidic pH range (6-6.9) and NADPH at the alkaline range (8.5-8.7). NADPH, however, is the probable reactant in biological systems.
Protein Name Biliverdin Reductase A
Bvr A
Biliverdin-Ix Alpha-Reductase
Database Links Reactome: R-HSA-189483
Reactome: R-HSA-9707564
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Biliverdin Reductase A antibody
Anti-Bvr A antibody
Anti-Biliverdin-Ix Alpha-Reductase antibody
Anti-BLVRA antibody
Anti-BLVR antibody
Anti-BVR antibody

Information sourced from Uniprot.org

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