| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARSL |
| Gene ID: | 415 |
| Uniprot ID: | ARSL_HUMAN |
| Immunogen Region: | 520-589 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-589 of human ARSE (NP_000038.2). |
| Immunogen Sequence: | PSETHILTPASEPVFYQVME RVQQAVWEHQRTLSPVPLQL DRLGNIWRPWLQPCCGPFPL CWCLREDDPQ |
| Tissue Specificity | Expressed in the pancreas, liver and kidney. |
| Post Translational Modifications | N-glycosylated. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
| Function | Exhibits arylsulfatase activity towards the artificial substrate 4-methylumbelliferyl sulfate. May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates. |
| Protein Name | Arylsulfatase LArylsulfatase EAse |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-9840310 |
| Cellular Localisation | Golgi ApparatusGolgi Stack |
| Alternative Antibody Names | Anti-Arylsulfatase L antibodyAnti-Arylsulfatase E antibodyAnti-Ase antibodyAnti-ARSL antibodyAnti-ARSE antibody |
Information sourced from Uniprot.org