| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Aquaporin-7 (136-186 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AQP7 |
| Gene ID: |
364 |
| Uniprot ID: |
AQP7_HUMAN |
| Immunogen Region: |
136-186 aa |
| Specificity: |
This antibody detects endogenous levels of AQP7 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human AQP7 at the amino acid range 136-186 |
| Post Translational Modifications | Phosphorylation by PKA could prevent the interaction with PLIN1. |
| Function | Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Mediates the efflux of glycerol, formed upon triglyceride hydrolysis, to avoid its accumulation in adipocytes and to make it available to other tissues. In the kidney, mediates the reabsorption of glycerol, preventing its loss in urine, again participating to energy homeostasis. In pancreatic beta cells, it also mediates the efflux of glycerol, regulating its intracellular levels. |
| Protein Name | Aquaporin-7Aqp-7Aquaglyceroporin-7Aquaporin AdiposeAqpapAquaporin-7-Like |
| Database Links | Reactome: R-HSA-432030Reactome: R-HSA-432047 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembraneLipid DropletInternalized From The Cell Membrane In Response To Catecholamine-Induced Activation Of PkaDetected On Intracellular Membranes And Colocalizes With Lipid DropletsColocalizes With Plin1 In AdipocytesProbably On Lipid Droplets |
| Alternative Antibody Names | Anti-Aquaporin-7 antibodyAnti-Aqp-7 antibodyAnti-Aquaglyceroporin-7 antibodyAnti-Aquaporin Adipose antibodyAnti-Aqpap antibodyAnti-Aquaporin-7-Like antibodyAnti-AQP7 antibodyAnti-AQP7L antibodyAnti-AQP9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
