| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-APOBEC1 (1-80) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
APOBEC1 |
| Gene ID: |
339 |
| Uniprot ID: |
ABEC1_HUMAN |
| Immunogen Region: |
1-80 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human APOBEC1 (NP_001291495). |
| Immunogen Sequence: |
MTSEKGPSTGDPTLRRRIEP WEFDVFYDPRELRKEACLLY EIKWGMSRKIWRSSGKNTTN HVEVNFIKKFTSERDFHPSM |
| Tissue Specificity | Expressed exclusively in the small intestine. |
| Function | Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs. Form complexes with cofactors that confer differential editing activity and selectivity. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. |
| Protein Name | C->U-Editing Enzyme Apobec-1Apolipoprotein B Mrna-Editing Enzyme Catalytic Subunit 1Apo1Apobec-1Apolipoprotein B Mrna-Editing Enzyme 1HeprMrna(Cytosine(6666 Deaminase 1 |
| Database Links | Reactome: R-HSA-72200Reactome: R-HSA-75094 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-C->U-Editing Enzyme Apobec-1 antibodyAnti-Apolipoprotein B Mrna-Editing Enzyme Catalytic Subunit 1 antibodyAnti-Apo1 antibodyAnti-Apobec-1 antibodyAnti-Apolipoprotein B Mrna-Editing Enzyme 1 antibodyAnti-Hepr antibodyAnti-Mrna(Cytosine(6666 Deaminase 1 antibodyAnti-APOBEC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
