| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AP-4 complex subunit sigma-1 (69-119 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AP4S1 |
| Gene ID: |
11154 |
| Uniprot ID: |
AP4S1_HUMAN |
| Immunogen Region: |
69-119 aa |
| Specificity: |
This antibody detects endogenous levels of human AP4S1 |
| Immunogen: |
Synthesized peptide derived from the human AP4S1 at the amino acid range 69-119 |
| Function | Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (Probable). |
| Protein Name | Ap-4 Complex Subunit Sigma-1Ap-4 Adaptor Complex Subunit Sigma-1Adaptor-Related Protein Complex 4 Subunit Sigma-1Sigma-1 Subunit Of Ap-4Sigma-4-AdaptinSigma4-Adaptin |
| Database Links | Reactome: R-HSA-432720 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Ap-4 Complex Subunit Sigma-1 antibodyAnti-Ap-4 Adaptor Complex Subunit Sigma-1 antibodyAnti-Adaptor-Related Protein Complex 4 Subunit Sigma-1 antibodyAnti-Sigma-1 Subunit Of Ap-4 antibodyAnti-Sigma-4-Adaptin antibodyAnti-Sigma4-Adaptin antibodyAnti-AP4S1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
