| Function | Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (Probable). |
| Protein Name | Ap-4 Complex Subunit Sigma-1Ap-4 Adaptor Complex Subunit Sigma-1Adaptor-Related Protein Complex 4 Subunit Sigma-1Sigma-1 Subunit Of Ap-4Sigma-4-AdaptinSigma4-Adaptin |
| Database Links | Reactome: R-HSA-432720 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Ap-4 Complex Subunit Sigma-1 antibodyAnti-Ap-4 Adaptor Complex Subunit Sigma-1 antibodyAnti-Adaptor-Related Protein Complex 4 Subunit Sigma-1 antibodyAnti-Sigma-1 Subunit Of Ap-4 antibodyAnti-Sigma-4-Adaptin antibodyAnti-Sigma4-Adaptin antibodyAnti-AP4S1 antibody |
Information sourced from Uniprot.org
