| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | ANKRD6 |
| Gene ID: | 22881 |
| Uniprot ID: | ANKR6_HUMAN |
| Immunogen Region: | 423-722 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 423-722 of human ANKRD6 (NP_055757.3). |
| Immunogen Sequence: | NQLEATVEEIKAELGSVQDK MNTKLGQMENKTQHQMRVLD KLMVERLSAERTECLNRLQQ HSDTEKHEGEKRQISLVDEL KTWCMLKIQNLEQKLSGDSR ACRAKSTPSTCVDQLVVTAG PAAASDSSPPVVRPKEKALN STATQRLQQELSSSDCTGSR LRNVKVQTALLPMNEAARSD QQAGPCVNRGTQTKKSGKSG PTRHRAQQPAASSTCGQPPP ATGSEQTGPHIRDTSQALE |
| Function | Recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-catenin, thereby inhibiting beta-catenin/Tcf signals. |
| Protein Name | Ankyrin Repeat Domain-Containing Protein 6Diversin |
| Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 6 antibodyAnti-Diversin antibodyAnti-ANKRD6 antibodyAnti-KIAA0957 antibody |
Information sourced from Uniprot.org