Western blot analysis of lysates from mouse pancreas, using ALDH1A3 Rabbit polyclonal antibody (STJ117424) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-ALDH1A3 antibody (1-140) (STJ117424)

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STJ117424
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ALDH1A3
Gene ID: 220
Uniprot ID: AL1A3_HUMAN
Immunogen Region: 1-140
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ALDH1A3 (NP_000684.2).
Immunogen Sequence: MATANGAVENGQPDRKPPAL PRPIRNLEVKFTKIFINNEW HESKSGKKFATCNPSTREQI CEVEEGDKPDVDKAVEAAQV AFQRGSPWRRLDALSRGRLL HQLADLVERDRATLAALETM DTGKPFLHAFFIDLEGCIRT
Tissue Specificity Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
Function Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. High specificity for all-trans-retinal as substrate, can also accept acetaldehyde as substrate in vitro but with lower affinity. Required for the biosynthesis of normal levels of retinoate in the embryonic ocular and nasal regions.a critical lipid in the embryonic development of the eye and the nasal region.
Protein Name Retinaldehyde Dehydrogenase 3
Raldh-3
Raldh3
Aldehyde Dehydrogenase 6
Aldehyde Dehydrogenase Family 1 Member A3
Aldh1a3
Database Links Reactome: R-HSA-5365859
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Retinaldehyde Dehydrogenase 3 antibody
Anti-Raldh-3 antibody
Anti-Raldh3 antibody
Anti-Aldehyde Dehydrogenase 6 antibody
Anti-Aldehyde Dehydrogenase Family 1 Member A3 antibody
Anti-Aldh1a3 antibody
Anti-ALDH1A3 antibody
Anti-ALDH6 antibody

Information sourced from Uniprot.org

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