| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ALDH1A3 (1-140) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ALDH1A3 |
| Gene ID: |
220 |
| Uniprot ID: |
AL1A3_HUMAN |
| Immunogen Region: |
1-140 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ALDH1A3 (NP_000684.2). |
| Immunogen Sequence: |
MATANGAVENGQPDRKPPAL PRPIRNLEVKFTKIFINNEW HESKSGKKFATCNPSTREQI CEVEEGDKPDVDKAVEAAQV AFQRGSPWRRLDALSRGRLL HQLADLVERDRATLAALETM DTGKPFLHAFFIDLEGCIRT |
| Tissue Specificity | Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney. |
| Function | Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. High specificity for all-trans-retinal as substrate, can also accept acetaldehyde as substrate in vitro but with lower affinity. Required for the biosynthesis of normal levels of retinoate in the embryonic ocular and nasal regions.a critical lipid in the embryonic development of the eye and the nasal region. |
| Protein Name | Retinaldehyde Dehydrogenase 3Raldh-3Raldh3Aldehyde Dehydrogenase 6Aldehyde Dehydrogenase Family 1 Member A3Aldh1a3 |
| Database Links | Reactome: R-HSA-5365859 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Retinaldehyde Dehydrogenase 3 antibodyAnti-Raldh-3 antibodyAnti-Raldh3 antibodyAnti-Aldehyde Dehydrogenase 6 antibodyAnti-Aldehyde Dehydrogenase Family 1 Member A3 antibodyAnti-Aldh1a3 antibodyAnti-ALDH1A3 antibodyAnti-ALDH6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
