| Tissue Specificity | Detected in cerebrospinal fluid (at protein level). Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines. |
| Post Translational Modifications | Glycosylated. Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. Additionally, furin is involved in the cleavage at another site, in the middle of the extracellular domain, generating a soluble fragment. |
| Function | Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition. |
| Protein Name | Adhesion G Protein-Coupled Receptor B2Brain-Specific Angiogenesis Inhibitor 2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinSecreted |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor B2 antibodyAnti-Brain-Specific Angiogenesis Inhibitor 2 antibodyAnti-ADGRB2 antibodyAnti-BAI2 antibody |
Information sourced from Uniprot.org
