Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-AGRB2 (700-800) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ADGRB2 |
Gene ID: |
576 |
Uniprot ID: |
AGRB2_HUMAN |
Immunogen Region: |
700-800 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AGRB2 (NP_001281264.1). |
Immunogen Sequence: |
DFIHLVGDALKAFQSSLIVT DNLVISIQREPVSAVSSDIT FPMRGRRGMKDWVRHSEDRL FLPKEVLSLSSPGKPATSGA AGSPGRGRGPGTVPPGPGHS H |
Tissue Specificity | Detected in cerebrospinal fluid (at protein level). Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines. |
Post Translational Modifications | Autoproteolytically processed at the GPS domain.this cleavage modulates receptor activity. Additionally, furin is involved in the cleavage at another site, in the middle of the extracellular domain, generating a soluble fragment. Glycosylated. |
Function | Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition. |
Protein Name | Adhesion G Protein-Coupled Receptor B2Brain-Specific Angiogenesis Inhibitor 2 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinSecreted |
Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor B2 antibodyAnti-Brain-Specific Angiogenesis Inhibitor 2 antibodyAnti-ADGRB2 antibodyAnti-BAI2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance