Tissue Specificity | Widely expressed. |
Function | Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable. |
Protein Name | 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Epsilon1-Acylglycerol-3-Phosphate O-Acyltransferase 51-Agp Acyltransferase 51-Agpat 5Lysophosphatidic Acid Acyltransferase EpsilonLpaat-Epsilon |
Database Links | Reactome: R-HSA-1483166 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinNucleus EnvelopeMitochondrion |
Alternative Antibody Names | Anti-1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Epsilon antibodyAnti-1-Acylglycerol-3-Phosphate O-Acyltransferase 5 antibodyAnti-1-Agp Acyltransferase 5 antibodyAnti-1-Agpat 5 antibodyAnti-Lysophosphatidic Acid Acyltransferase Epsilon antibodyAnti-Lpaat-Epsilon antibodyAnti-AGPAT5 antibody |
Information sourced from Uniprot.org