Anti-Adenylate Cyclase 10 antibody (200-250) {Biotin} (STJ502868)

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STJ502868-100
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Gorilla/Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Adenylate Cyclase 10 (200-250) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Biotin
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.55-0.75 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Adcy10
Gene ID: 271639
Uniprot ID: ADCYA_MOUSE
Immunogen Region: 200-250
Immunogen: Synthetic peptide taken within amino acid region 200-250 on mouse Adenylate Cyclase type 10 protein.
Tissue Specificity Expressed in testis.
Function Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation.
Protein Name Adenylate Cyclase Type 10
Germ Cell Soluble Adenylyl Cyclase
Sac
Testicular Soluble Adenylyl Cyclase
Database Links Reactome: R-MMU-5610787
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasm
Cytoskeleton
Perinuclear Region
Nucleus
Cell Projection
Cilium
Mitochondrion
Distributed To Subcellular Compartments Containing Camp Targets
Found As A Plasma Membrane-Associated Protein
Protein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin
Alternative Antibody Names Anti-Adenylate Cyclase Type 10 antibody
Anti-Germ Cell Soluble Adenylyl Cyclase antibody
Anti-Sac antibody
Anti-Testicular Soluble Adenylyl Cyclase antibody
Anti-Adcy10 antibody
Anti-Sac antibody
Anti-Sacy antibody

Information sourced from Uniprot.org

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