| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-ABCB9/TAPL (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments gave no signal but low background in human brain and liver lysates at up to 1µg/ml. We would appreciate any feedback from people in the field-have any results b |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ABCB9 |
| Gene ID: | 23457 |
| Uniprot ID: | ABCB9_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_062570.1; NP_062571.1; NP_982269.1 |
| Specificity: | This antibody is expected to recognise both human isoforms of this protein (as represented by NP_062570.1, NP_062571.1and NP_982269.1). Variants (NP_062571.1; NP_982269.1) encode the same isoform. |
| Immunogen Sequence: | GHNEPVANGSHKA |
| Function | ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen for degradation. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Binds and transports smaller and larger peptides with the same affinity. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. |
| Protein Name | Abc-Type Oligopeptide Transporter Abcb9Atp-Binding Cassette Sub-Family B Member 9Atp-Binding Cassette Transporter 9Abc Transporter 9 ProteinHabcb9Tap-Like ProteinTapl |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinMay Be Located In Membrane RaftsTakes An Intracellular Route From The Endoplasmic Reticulum (Er)Via Golgi And Early Endosomes To Late Endosomal And Lysosomal Compartments |
| Alternative Antibody Names | Anti-Abc-Type Oligopeptide Transporter Abcb9 antibodyAnti-Atp-Binding Cassette Sub-Family B Member 9 antibodyAnti-Atp-Binding Cassette Transporter 9 antibodyAnti-Abc Transporter 9 Protein antibodyAnti-Habcb9 antibodyAnti-Tap-Like Protein antibodyAnti-Tapl antibodyAnti-ABCB9 antibodyAnti-KIAA1520 antibody |
Information sourced from Uniprot.org