| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AADAC (170-399) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AADAC |
| Gene ID: |
13 |
| Uniprot ID: |
AAAD_HUMAN |
| Immunogen Region: |
170-399 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 170-399 of human AADAC (NP_001077.2). |
| Immunogen Sequence: |
KKVLAKYGVNPERIGISGDS AGGNLAAAVTQQLLDDPDVK IKLKIQSLIYPALQPLDVDL PSYQENSNFLFLSKSLMVRF WSEYFTTDRSLEKAMLSRQH VPVESSHLFKFVNWSSLLPE RFIKGHVYNNPNYGSSELAK KYPGFLDVRAAPLLADDNKL RGLPLTYVITCQYDLLRDDG LMYVTRLRNTGVQVTHNHVE DGFHGAFSFLGLKISHRLIN QYIEWLKENL |
| Tissue Specificity | Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder. |
| Post Translational Modifications | Glycosylation is required for enzyme activity. |
| Function | Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. |
| Protein Name | Arylacetamide Deacetylase |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinMicrosome Membrane |
| Alternative Antibody Names | Anti-Arylacetamide Deacetylase antibodyAnti-AADAC antibodyAnti-DAC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
