Mouse PLUNC (Palate/Lung And Nasal Epithelium Associated Protein) Ready-To-Use Sandwich ELISA Kit (STJE0017957)

Mouse PLUNC (Palate/Lung And Nasal Epithelium Associated Protein) Ready-To-Use Sandwich ELISA Kit (STJE0017957)

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STJE0017957
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.061ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This PLUNC Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids.
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Bpifa1
Gene ID: 18843
Uniprot ID: BPIA1_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Detected in airway epithelia (trachea and lung) and in bronchoalveolar fluid (at protein level). Upper airways, nasopharyngeal epithelium and thymus. Highest expression in the trachea and progressive decrease from proximal (bronchial) to distal (bronchiolar) airways. No expression is detected in the terminal bronchioles, respiratory bronchioles or lung alveoli.
Post Translational Modifications
Function Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils.
Protein Name Bpi Fold-Containing Family A Member 1
Palate Lung And Nasal Epithelium Clone Protein
Database Links Reactome: R-MMU-6803157
Cellular Localisation Secreted
Apical Side Of Airway Epithelial Cells
Detected In Airway Surface Liquid
Nasal Mucus And Sputum
Alternative ELISA Names Bpi Fold-Containing Family A Member 1 ELISA kit
Palate Lung And Nasal Epithelium Clone Protein ELISA kit
Bpifa1 ELISA kit
Plunc ELISA kit
Splunc1 ELISA kit
output

Information sourced from Uniprot.org

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