Mouse FNDC5 protein (Recombinant) (N-His) (STJP010493)

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STJP010493
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse FNDC5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Fndc5
Gene ID: 384061
Uniprot ID: FNDC5_MOUSE
Immunogen Region: Met73-Lys208
Immunogen: Mus musculus (Mouse)
Post Translational Modifications The extracellular domain is cleaved and released from the cell membrane. N-Glycosylated.
Function Irisin: Mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.
Protein Name Fibronectin Type Iii Domain-Containing Protein 5
Fibronectin Type Iii Repeat-Containing Protein 2
Peroxisomal Protein
Pep Cleaved Into - Irisin
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Peroxisome Membrane
Secreted
Imported In Peroxisomes Through The Pex5 Receptor Pathway
Irisin: Secreted
Detected In The Blood Of Individuals Subjected To Endurance Exercise
Alternative Protein Names Fibronectin Type Iii Domain-Containing Protein 5 protein
Fibronectin Type Iii Repeat-Containing Protein 2 protein
Peroxisomal Protein protein
Pep Cleaved Into - Irisin protein
Fndc5 protein
Frcp2 protein
Pep protein

Information sourced from Uniprot.org

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