Function | Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms. |
Protein Name | Ep300-Interacting Inhibitor Of Differentiation 1Crebbp/Ep300 Inhibitory Protein 1E1a-Like Inhibitor Of Differentiation 1Eid-1 |
Cellular Localisation | NucleusCytoplasmMay Shuttle Between Nucleus And Cytoplasm |
Alternative Protein Names | Ep300-Interacting Inhibitor Of Differentiation 1 proteinCrebbp/Ep300 Inhibitory Protein 1 proteinE1a-Like Inhibitor Of Differentiation 1 proteinEid-1 proteinEid1 proteinCri1 protein |
Information sourced from Uniprot.org