Tissue Specificity | Expressed in testis, epididymis, and bone marrow, as well as in Sertoli and promyelocytic cell lines. Upon stimulation with different TLR ligands, it is strongly expressed in granulocytes and in bone marrow-derived dendritic cells. |
Post Translational Modifications | |
Function | The cytotoxic action of BPI is limited to many species of Gram-negative bacteria.this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. |
Protein Name | Bactericidal Permeability-Increasing ProteinBpi |
Database Links | Reactome: R-MMU-166016Reactome: -MMU-6798695Reactome: -MMU-6803157 |
Cellular Localisation | SecretedCytoplasmic Granule MembraneMembrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules |
Alternative ELISA Names | Bactericidal Permeability-Increasing Protein ELISA kitBpi ELISA kitBpi ELISA kit |
output | |
Information sourced from Uniprot.org