Human UNC13D protein (Recombinant) (N-His) (STJP008769)

SKU:
STJP008769
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human UNC13D-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: UNC13D
Gene ID: 201294
Uniprot ID: UN13D_HUMAN
Immunogen Region: Ser888-Pro1090
Immunogen: Homo sapiens (Human)
Function Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
Protein Name Protein Unc-13 Homolog D
Munc13-4
Database Links Reactome: R-HSA-6798695
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
Late Endosome
Recycling Endosome
Lysosome
Colocalizes With Cytotoxic Granules At The Plasma Membrane
Localizes To Endosomal Exocytic Vesicles
Alternative Protein Names Protein Unc-13 Homolog D protein
Munc13-4 protein
UNC13D protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP002980 Human KLHL20 protein (Recombinant) (N-His) (STJP002980) HEK293 cells
STJP003027 Human CCL3L1 protein (Recombinant) (N-His) (STJP003027) HEK293 cells
STJP003488 Human CFD protein (Recombinant) (N-His) (STJP003488) E. coli

Related Products

!