Human ROR1 (Receptor Tyrosine Kinase Like Orphan Receptor 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018320)

Human ROR1 (Receptor Tyrosine Kinase Like Orphan Receptor 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018320)

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STJE0018320
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.054ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This ROR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: ROR1
Gene ID: 4919
Uniprot ID: ROR1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.
Post Translational Modifications
Function Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling.
Protein Name Inactive Tyrosine-Protein Kinase Transmembrane Receptor Ror1
Neurotrophic Tyrosine Kinase - Receptor-Related 1
Database Links Reactome: R-HSA-5140745
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Axon
Alternative ELISA Names Inactive Tyrosine-Protein Kinase Transmembrane Receptor Ror1 ELISA kit
Neurotrophic Tyrosine Kinase - Receptor-Related 1 ELISA kit
ROR1 ELISA kit
NTRKR1 ELISA kit
output

Information sourced from Uniprot.org

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