• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using QSK Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of LOVO cells using QSK Polyclonal Antibody

Anti-QSK antibody (STJ95283)

SKU:
STJ95283

Current Stock:
Host: Rabbit
Applications: WB, IHC-P, ELISA
Reactivity: Human, Mouse
Short Description: Rabbit polyclonal anti-QSK antibody is suitable for use in Western Blot, Immunohistochemistry and ELISA.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Specificity: QSK polyclonal antibody detects endogenous levels of QSK protein.
Uniprot ID: SIK3_HUMAN
Gene ID: 23387
Gene Symbol: SIK3
Immunogen: Synthesized peptide derived from human QSK
Immunogen Region: 490-570 aa, Internal
Post Translational Modifications Phosphorylated at Thr-221 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Phosphorylation at Thr-221 is inhibited in response to PTHLH/PTHrP. Phosphorylated at Thr-469 and Ser-551 in response to cAMP signaling (Probable).
Function Positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor. Involved in the dynamic regulation of mTOR signaling in chondrocyte differentiation during skeletogenesis. Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3 (Probable). Prevents HDAC4 translocation to the nucleus.
Protein Name Serine/Threonine-Protein Kinase Sik3
Salt-Inducible Kinase 3
Sik-3
Serine/Threonine-Protein Kinase Qsk
Cellular Localisation Cytoplasm
Locates To Punctate Structures Within The Cytoplasm On Binding To Ywhaz
Alternative Antibody Names Anti-Serine/Threonine-Protein Kinase Sik3 antibody
Anti-Salt-Inducible Kinase 3 antibody
Anti-Sik-3 antibody
Anti-Serine/Threonine-Protein Kinase Qsk antibody
Anti-SIK3 antibody
Anti-KIAA0999 antibody
Anti-QSK antibody
Anti-L19 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance