• Immunofluorescence analysis of MCF7 cells using LGALS3BP antibody (STJ29009). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using LGALS3BP antibody (STJ29009) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.

Anti-LGALS3BP antibody (STJ29009)

SKU:
STJ29009
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Host: Rabbit
Applications: WB, IF
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal primary antibody against LGALS3BP.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage Instruction: Store at-20°C. Avoid freeze/thaw cycles.
Isotype: IgG
Dilution Range: WB: 1:500-1:2000
IF: 1:50-1:100
Uniprot ID: LG3BP_HUMAN
Gene ID: 3959
Gene Symbol: LGALS3BP
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 306-585 of human LGALS3BP (NP_005558.1).
Background The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
Tissue Specificity Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts.
Function Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
Database Links Reactome: R-HSA-114608
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Protein Name Galectin-3-Binding Protein
Basement Membrane Autoantigen P105
Lectin Galactoside-Binding Soluble 3-Binding Protein
Mac-2-Binding Protein
Mac2bp
Mac-2 Bp
Tumor-Associated Antigen 90k
Alternative Names Anti-Galectin-3-Binding Protein antibody
Anti-Basement Membrane Autoantigen P105 antibody
Anti-Lectin Galactoside-Binding Soluble 3-Binding Protein antibody
Anti-Mac-2-Binding Protein antibody
Anti-Mac2bp antibody
Anti-Mac-2 Bp antibody
Anti-Tumor-Associated Antigen 90k antibody
Anti-LGALS3BP antibody
Anti-M2BP antibody

Information sourced from uniprot.org

6 months standard