| Post Translational Modifications | Phosphorylated by GRK4 (GRK4-alpha and GRK4-gamma). Palmitoylated. |
| Function | Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation. |
| Protein Name | D(3 Dopamine ReceptorDopamine D3 Receptor |
| Database Links | Reactome: R-HSA-390651Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBoth Membrane-Bound And Scattered In The Cytoplasm During Basal ConditionsReceptor Stimulation Results In The Rapid Internalization And Sequestration Of The Receptors At The Perinuclear Area (5 And 15 Minutes)Followed By The Dispersal Of The Receptors To The Membrane (30 Minutes)Drd3 And Grk4 Co-Localize In Lipid Rafts Of Renal Proximal Tubule Cells |
| Alternative Antibody Names | Anti-D(3 Dopamine Receptor antibodyAnti-Dopamine D3 Receptor antibodyAnti-DRD3 antibody |
Information sourced from Uniprot.org
