| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CCR4-NOT transcription complex subunit 9 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CNOT9 |
| Gene ID: |
9125 |
| Uniprot ID: |
CNOT9_HUMAN |
| Specificity: |
This antibody detects endogenous levels of CNOT9 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human CNOT9 |
| Function | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation. Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all. |
| Protein Name | Ccr4-Not Transcription Complex Subunit 9Cell Differentiation Protein Rqcd1 HomologRcd-1 |
| Database Links | Reactome: R-HSA-429947Reactome: R-HSA-5617472Reactome: R-HSA-6804115 |
| Cellular Localisation | NucleusCytoplasmP-BodyNanos2 Promotes Its Localization To P-Body |
| Alternative Antibody Names | Anti-Ccr4-Not Transcription Complex Subunit 9 antibodyAnti-Cell Differentiation Protein Rqcd1 Homolog antibodyAnti-Rcd-1 antibodyAnti-CNOT9 antibodyAnti-RCD1 antibodyAnti-RQCD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
