||Human, Mouse, Rat
||FOR RESEARCH USE ONLY (RUO).
||Rabbit polyclonal antibody anti-Acetyl-Cyclin-Dependent Kinase Inhibitor 1c-Lys278 (241-290) is suitable for use in Western Blot and ELISA research applications.
||PBS, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
||The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
||WB 1:500-1:2000ELISA 1:20000
||Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
||Acetyl-CDKN1C-Lys278 polyclonal antibody (Cyclin-Dependent Kinase Inhibitor 1c) binds to endogenous Cyclin-Dependent Kinase Inhibitor 1c at the amino acid region 241-290.
||The antiserum was produced against synthesized Acetyl-peptide derived from human p57Kip2 around the Acetylation site of Lys278 at amino acid range 241-290
| Function || Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
| Protein Name || Cyclin-Dependent Kinase Inhibitor 1cCyclin-Dependent Kinase Inhibitor P57P57kip2 |
| Database Links || Reactome: R-HSA-69231Reactome: R-HSA-9661069 |
| Cellular Localisation || Nucleus |
| Alternative Antibody Names || Anti-Cyclin-Dependent Kinase Inhibitor 1c antibodyAnti-Cyclin-Dependent Kinase Inhibitor P57 antibodyAnti-P57kip2 antibodyAnti-CDKN1C antibodyAnti-KIP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance