||Human, Rat, Mouse
||FOR RESEARCH USE ONLY (RUO).
||Rabbit polyclonal antibody anti-Atp-Binding Cassette Sub-Family D Member 2 (310-390) is suitable for use in Western Blot and ELISA research applications.
||PBS, 50% Glycerol and 0.02% Sodium Azide.
||The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
||WB 1:500-2000ELISA 1:5000-20000
||Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
||ABCD2 polyclonal antibody (Atp-Binding Cassette Sub-Family D Member 2) binds to endogenous Atp-Binding Cassette Sub-Family D Member 2 at the amino acid region 310-390.
||Synthesized peptide derived from human protein at aa range 310-390
| Function || ATP-dependent transporter of the ATP-binding cassette (ABC) family involved in the transport of very long chain fatty acid (VLCFA)-CoA from the cytosol to the peroxisome lumen. Like ABCD1 seems to have fatty acyl-CoA thioesterase (ACOT) and ATPase activities, according to this model, VLCFA-CoA as free VLCFA is transpoted in an ATP-dependent manner into peroxisomes after the hydrolysis of VLCFA-CoA mediated by the ACOT activity of ABCD2 (Probable). Shows overlapping substrate specificities with ABCD1 toward saturated fatty acids (FA) and monounsaturated FA (MUFA) but has a distinct substrate preference for shorter VLCFA (C22:0) and polyunsaturated fatty acid (PUFA) such as C22:6-CoA and C24:6-CoA (in vitro). Thus, may play a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation. |
| Protein Name || Atp-Binding Cassette Sub-Family D Member 2Adrenoleukodystrophy-Like 1Adrenoleukodystrophy-Related ProteinHaldr |
| Database Links || Reactome: R-HSA-1369062Reactome: R-HSA-9603798 |
| Cellular Localisation || Peroxisome MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names || Anti-Atp-Binding Cassette Sub-Family D Member 2 antibodyAnti-Adrenoleukodystrophy-Like 1 antibodyAnti-Adrenoleukodystrophy-Related Protein antibodyAnti-Haldr antibodyAnti-ABCD2 antibodyAnti-ALD1 antibodyAnti-ALDL1 antibodyAnti-ALDR antibodyAnti-ALDRP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance