• Absorbance analysis at 450nm using Mouse PRF1 ELISA Kit.

Mouse PRF1 Sandwich ELISA Kit (STJ150305)

SKU:
STJ150305

Current Stock:
Applications: ELISA
Reactivity: Mouse
Short Description: This Mouse PRF1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Note: FOR RESEARCH USE ONLY (RUO).
Sensitivity: 10ng/mL
Detection Limit: 0.156--10ng/mL
Storage Instruction: Store at 4°C for 6 months.
Uniprot ID: PERF_HUMAN
Gene ID: 5551
Gene Symbol: PRF1
Sample Type: Serum, Plasma, Biological Fluids
Function Pore-forming protein that plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Protein Name Perforin-1
P1
Cytolysin
Lymphocyte Pore-Forming Protein
Pfp
Cellular Localisation Cytoplasmic Granule Lumen
Secreted
Cell Membrane
Multi-Pass Membrane Protein
Endosome Lumen
Stored In Cytoplasmic Granules Of Cytolytic T-Lymphocytes And Secreted Into The Cleft Between T-Lymphocyte And Target Cell
Inserts Into The Cell Membrane Of Target Cells And Forms Pores
Membrane Insertion And Pore Formation Requires A Major Conformation Change
May Be Taken Up Via Endocytosis Involving Clathrin-Coated Vesicles And Accumulate In A First Time In Large Early Endosomes
Alternative ELISA Kit Names Perforin-1 ELISA kit
P1 ELISA kit
Cytolysin ELISA kit
Lymphocyte Pore-Forming Protein ELISA kit
Pfp ELISA kit
PRF1 ELISA kit
PFP ELISA kit

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance