Mouse MCP-1 (C-C Motif Chemokine 2) Antibody Pair (STJAP00079)
SPECIFICATIONS
ClonalityPolyclonal/Polyclonal
HostGoat/Goat
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Mouse MCP-1 protein.Detection Immunogen: Recombinant Mouse MCP-1 protein.
General Information
| Short Description | This MCP-1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Ccl2 |
| Gene ID | 20296 |
| Uniprot ID | CCL2_MOUSE |
| Immunogen | Capture immunogen: Recombinant Mouse MCP-1 protein.Detection Immunogen: Recombinant Mouse MCP-1 protein. |
Additional Info
| Function | Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. Plays an important role in mediating peripheral nerve injury-induced neuropathic pain. Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B. |
| Protein Name | C-C Motif Chemokine 2Monocyte Chemoattractant Protein 1Monocyte Chemotactic Protein 1Mcp-1Platelet-Derived Growth Factor-Inducible Protein JeSmall-Inducible Cytokine A2 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-C Motif Chemokine 2 antibody pairMonocyte Chemoattractant Protein 1 antibody pairMonocyte Chemotactic Protein 1 antibody pairMcp-1 antibody pairPlatelet-Derived Growth Factor-Inducible Protein Je antibody pairSmall-Inducible Cytokine A2 antibody pairCcl2 antibody pairJe antibody pairMcp1 antibody pairScya2 antibody pair |
Information sourced from Uniprot.org