Tissue Specificity | Bone marrow cells. Neutrophil. |
Function | Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro.digests outer membrane protein A (ompA) in E.coli and K.pneumoniae. |
Database Links | Reactome: R-HSA-1442490 |
Cellular Localisation | Cytoplasmic VesiclePhagosomeLocalized In Phagolysosomes Following Ingestion Of EColi By Neutrophils |
Protein Name | Neutrophil ElastaseBone Marrow Serine ProteaseElastase-2Human Leukocyte ElastaseHleMedullasinPmn Elastase |
Alternative Names | Anti-Neutrophil Elastase antibodyAnti-Bone Marrow Serine Protease antibodyAnti-Elastase-2 antibodyAnti-Human Leukocyte Elastase antibodyAnti-Hle antibodyAnti-Medullasin antibodyAnti-Pmn Elastase antibodyAnti-ELANE antibodyAnti-ELA2 antibody |
Information sourced from Uniprot.org