Host: | Mammalian Cells |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human SERPINF2/Alpha 2-antiplasmin-C-Strep protein was developed from mammalian cells and has a target region of C-Strep. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | SERPINF2 |
Gene ID: | 5345 |
Uniprot ID: | A2AP_HUMAN |
Immunogen Region: | Met1-Lys491 |
Immunogen: | Homo sapiens (Human) |
Post Translational Modifications | Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin. |
Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. |
Protein Name | Alpha-2-AntiplasminAlpha-2-ApAlpha-2-Plasmin InhibitorAlpha-2-PiSerpin F2 |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-75205 |
Cellular Localisation | Secreted |
Alternative Protein Names | Alpha-2-Antiplasmin proteinAlpha-2-Ap proteinAlpha-2-Plasmin Inhibitor proteinAlpha-2-Pi proteinSerpin F2 proteinSERPINF2 proteinAAP proteinPLI protein |
Information sourced from Uniprot.org