Human OLIG2 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007386)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human OLIG2-N-His-SUMO & C-Strep protein was developed from e.coli for the region N-His-SUMO & C-Strep. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | OLIG2 |
| Gene ID | 10215 |
| Uniprot ID | OLIG2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr102-His180 |
Additional Info
| Function | Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. |
| Protein Name | Oligodendrocyte Transcription Factor 2Oligo2Class B Basic Helix-Loop-Helix Protein 1Bhlhb1Class E Basic Helix-Loop-Helix Protein 19Bhlhe19Protein Kinase C-Binding Protein 2Protein Kinase C-Binding Protein Rack17 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmThe Nls Contained In The Bhlh Domain Could Be Masked In The Native Form And Translocation To The Nucleus Could Be Mediated By Interaction Either With Class E Bhlh Partner Protein Or With Nkx2-2 |
| Alternative Protein Names | Oligodendrocyte Transcription Factor 2 proteinOligo2 proteinClass B Basic Helix-Loop-Helix Protein 1 proteinBhlhb1 proteinClass E Basic Helix-Loop-Helix Protein 19 proteinBhlhe19 proteinProtein Kinase C-Binding Protein 2 proteinProtein Kinase C-Binding Protein Rack17 proteinOLIG2 proteinBHLHB1 proteinBHLHE19 proteinPRKCBP2 proteinRACK17 protein |
Information sourced from Uniprot.org