Human MYOZ1 protein (Recombinant) (His-Tag) (STJP018367)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MYOZ1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYOZ1 |
| Gene ID | 58529 |
| Uniprot ID | MYOZ1_HUMAN |
| Accession Number | NP_067068 |
| Immunogen | Human |
| Immunogen Region | 1-299aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMPLSGTP APNKKRKSSK LIMELTGGGQ ESSGLNLGKK ISVPRDVMLE ELSLLTNRGS KMFKLRQMRV EKFIYENHPD VFSDSSMDHF QKFLPTVGGQ LGTAGQGFSY SKSNGRGGSQ AGGSGSAGQY GSDQQHHLGS GSGAGGTGGP AGQAGRGGAA GTAGVGETGS GDQAGGEGKH ITVFKTYISP WERAMGVDPQ QKMELGID |
Additional Info
| Tissue Specificity | Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas. |
| Function | Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. |
| Protein Name | Myozenin-1Calsarcin-2Filamin- - Actinin- And Telethonin-Binding ProteinProtein Fatz |
| Database Links | |
| Cellular Localisation | NucleusCell ProjectionPseudopodiumLocalized To The Nucleus And Pseudopodia Of Undifferentiated Cells And Detected Throughout The Myotubes Of Differentiated CellsColocalizes With Actn2Flnc And Myot At The Z-Lines Of Skeletal Muscle |
| Alternative Protein Names | Myozenin-1 proteinCalsarcin-2 proteinFilamin- - Actinin- And Telethonin-Binding Protein proteinProtein Fatz proteinMYOZ1 proteinMYOZ protein |
Information sourced from Uniprot.org