Human MIP-3 beta (CCL19) protein (Recombinant) {Biotin} (STJP000215)

SKU:
STJP000215

Current Stock:
Host: E.coli
Applications: ELISA, WB
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Recombinant-Human MIP-3 beta (CCL19)-protein was developed from e.coli. For use in research applications.
Conjugation: Biotin
Formulation: Recombinant CCL19 was lyophilized from a.2 Mu m filteredmM PB, 100mM NaCl solution pH.5.
Dilution Range: Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction: The lyophilized protein is stable for at least years from date of receipt at-20°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8°C for one month, or at-20°C for six months, with a carrier protein without detectable loss
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: CCL19
Gene ID: 6363
Uniprot ID: CCL19_HUMAN
Immunogen Region: Mature chain
Immunogen Sequence: MKISVAAIPF FLLITIALGT KTESSSRGPY HPSECCFTYT TYKIPRQRIM DYYETNSQCS KPGIVFITKR GHSVCTNPSD KWVQDYIKDM KEN
Tissue Specificity Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
Function May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name C-C Motif Chemokine 19
Beta-Chemokine Exodus-3
Ck Beta-11
Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine
Ebi1 Ligand Chemokine
Elc
Macrophage Inflammatory Protein 3 Beta
Mip-3-Beta
Small-Inducible Cytokine A19
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6783783
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-C Motif Chemokine 19 antibody
Anti-Beta-Chemokine Exodus-3 antibody
Anti-Ck Beta-11 antibody
Anti-Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine antibody
Anti-Ebi1 Ligand Chemokine antibody
Anti-Elc antibody
Anti-Macrophage Inflammatory Protein 3 Beta antibody
Anti-Mip-3-Beta antibody
Anti-Small-Inducible Cytokine A19 antibody
Anti-CCL19 antibody
Anti-ELC antibody
Anti-MIP3B antibody
Anti-SCYA19 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance