Human MCP1 protein (Recombinant) {Biotin} (STJP000199)

SKU:
STJP000199

Current Stock:
Host: E.coli
Applications: ELISA, WB
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Recombinant-Human MCP1-protein was developed from e.coli. For use in research applications.
Conjugation: Biotin
Formulation: Recombinant SDF-1 alpha was lyophilized from a.2 Mu m filtered PBS, pH.4.
Dilution Range: Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction: The lyophilized protein is stable for at least years from date of receipt at-20°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8°C for one month, or at-20°C for six months, with a carrier protein without detectable loss
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: CCL2
Gene ID: 6347
Uniprot ID: CCL2_HUMAN
Immunogen Region: Mature chain
Tissue Specificity Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Expressed in monocytes.
Post Translational Modifications Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. N-Glycosylated.
Function Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Protein Name C-C Motif Chemokine 2
Hc11
Monocyte Chemoattractant Protein 1
Monocyte Chemotactic And Activating Factor
Mcaf
Monocyte Chemotactic Protein 1
Mcp-1
Monocyte Secretory Protein Je
Small-Inducible Cytokine A2
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-380994
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-C Motif Chemokine 2 antibody
Anti-Hc11 antibody
Anti-Monocyte Chemoattractant Protein 1 antibody
Anti-Monocyte Chemotactic And Activating Factor antibody
Anti-Mcaf antibody
Anti-Monocyte Chemotactic Protein 1 antibody
Anti-Mcp-1 antibody
Anti-Monocyte Secretory Protein Je antibody
Anti-Small-Inducible Cytokine A2 antibody
Anti-CCL2 antibody
Anti-MCP1 antibody
Anti-SCYA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance