Human MCP-3 (CCL7) protein (Recombinant) {Biotin} (STJP000209)


Current Stock:
Host: E.coli
Short Description: Recombinant-Human MCP-3 (CCL7)-protein was developed from e.coli. For use in research applications.
Conjugation: Biotin
Formulation: MCP-3 was lyophilized from a.2 Mu m filteredmM PB solution pH.5, mM NaCl.
Dilution Range: Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction: The lyophilized protein is stable for at least years from date of receipt at-20°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8°C for one month, or at-20°C for six months, with a carrier protein without detectable loss
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: CCL8
Gene ID: 6355
Uniprot ID: CCL8_HUMAN
Immunogen Region: Mature chain
Tissue Specificity Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
Post Translational Modifications N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Function Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Protein Name C-C Motif Chemokine 8
Monocyte Chemoattractant Protein 2
Monocyte Chemotactic Protein 2
Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-C Motif Chemokine 8 antibody
Anti-Hc14 antibody
Anti-Monocyte Chemoattractant Protein 2 antibody
Anti-Monocyte Chemotactic Protein 2 antibody
Anti-Mcp-2 antibody
Anti-Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 antibody
Anti-CCL8 antibody
Anti-MCP2 antibody
Anti-SCYA10 antibody
Anti-SCYA8 antibody

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