| Host: |
E.coli |
| Note: |
FOR RESEARCH USE ONLY (RUO). |
| Short Description: |
Recombinant-Human MCP-3 (CCL7)-protein was developed from e.coli. For use in research applications. |
| Conjugation: |
Biotin |
| Formulation: |
MCP-3 was lyophilized from a.2 Mu m filteredmM PB solution pH.5, mM NaCl. |
| Dilution Range: |
Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: |
The lyophilized protein is stable for at least years from date of receipt at-20°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8°C for one month, or at-20°C for six months, with a carrier protein without detectable loss |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
| Tissue Specificity | Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate. |
| Post Translational Modifications | N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. |
| Protein Name | C-C Motif Chemokine 8Hc14Monocyte Chemoattractant Protein 2Monocyte Chemotactic Protein 2Mcp-2Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 8 antibodyAnti-Hc14 antibodyAnti-Monocyte Chemoattractant Protein 2 antibodyAnti-Monocyte Chemotactic Protein 2 antibodyAnti-Mcp-2 antibodyAnti-Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 antibodyAnti-CCL8 antibodyAnti-MCP2 antibodyAnti-SCYA10 antibodyAnti-SCYA8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
