Human GZMM protein (Recombinant) (N-His) (STJP004859)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human GZMM-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | GZMM |
| Gene ID | 3004 |
| Uniprot ID | GRAM_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ile26-Ala257 |
Additional Info
| Function | Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells. |
| Protein Name | Granzyme MMet-1 Serine ProteaseHu-Met-1Met-AseNatural Killer Cell Granular Protease |
| Database Links | Reactome: R-HSA-173736 |
| Cellular Localisation | SecretedCytoplasmic GranuleGranules Of Large Granular Lymphocytes |
| Alternative Protein Names | Granzyme M proteinMet-1 Serine Protease proteinHu-Met-1 proteinMet-Ase proteinNatural Killer Cell Granular Protease proteinGZMM proteinMET1 protein |
Information sourced from Uniprot.org