Human FN3K protein (Recombinant) (N-His) (STJP005991)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human FN3K-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | FN3K |
| Gene ID | 64122 |
| Uniprot ID | FN3K_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Lys309 |
Additional Info
| Function | Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function. Also able to phosphorylate psicosamines and ribulosamines. |
| Protein Name | Fructosamine-3-KinaseProtein-Psicosamine 3-Kinase Fn3kProtein-Ribulosamine 3-Kinase Fn3k |
| Database Links | Reactome: R-HSA-163841 |
| Cellular Localisation | |
| Alternative Protein Names | Fructosamine-3-Kinase proteinProtein-Psicosamine 3-Kinase Fn3k proteinProtein-Ribulosamine 3-Kinase Fn3k proteinFN3K protein |
Information sourced from Uniprot.org