| Host: |
HEK293 Cells |
| Applications: |
SDS-PAGE/Bioactivity |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Recombinant-Human Fc gamma RIIA/CD32a (R167)-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications. |
| Formulation: |
Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: |
< 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity: |
Measured by its binding ability in a functional ELISA with Human IgG. |
| Gene Symbol: |
FCGR2A |
| Gene ID: |
2212 |
| Uniprot ID: |
FCG2A_HUMAN |
| Immunogen Region: |
30-218aa |
| Accession Number: |
AAA35827.1 |
| Immunogen: |
Human |
| Immunogen Sequence: |
SADSQAAAPP KAVLKLEPPW INVLQEDSVT LTCQGARSPE SDSIQWFHNG NLIPTHTQPS YRFKANNNDS GEYTCQTGQT SLSDPVHLTV LSEWLVLQTP HLEFQEGETI MLRCHSWKDK PLVKVTFFQN GKSQKFSRLD PTFSIPQANH SHSGDYHCTG NIGYTLFSSK PVTITVQVPS MGSSSPMGI |
| Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
| Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
| Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-AIgg Fc Receptor Ii-ACdw32Fc-Gamma Rii-AFc-Gamma-RiiaFcrii-ACd Antigen Cd32 |
| Database Links | Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A proteinIgg Fc Receptor Ii-A proteinCdw32 proteinFc-Gamma Rii-A proteinFc-Gamma-Riia proteinFcrii-A proteinCd Antigen Cd32 proteinFCGR2A proteinCD32 proteinFCG2 proteinFCGR2A1 proteinIGFR2 protein |
Information sourced from Uniprot.org
