Human CD16b/FCGR3B protein (Recombinant-Active) (C-His) (STJP012360)

Name: Human CD16b/FCGR3B protein (Recombinant-Active) (C-His) (STJP012360)
SKU: STJP012360-100
Price: 604.2 EUR
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP012360-100

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Short Description	Recombinant-Active-Human CD16b/FCGR3B-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3. The soluble form is produced by a proteolytic cleavage.
Function	Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Protein Name	Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B Fc-Gamma Riii-Beta Cd16-I Fc-Gamma Riii Fc-Gamma Riiib Fcriii Fcriiib Fcr-10 Igg Fc Receptor Iii-1 Cd Antigen Cd16b
Database Links	Reactome: R-HSA-163125 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Secreted Secreted After Cleavage
Alternative Protein Names	Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B protein Fc-Gamma Riii-Beta protein Cd16-I protein Fc-Gamma Riii protein Fc-Gamma Riiib protein Fcriii protein Fcriiib protein Fcr-10 protein Igg Fc Receptor Iii-1 protein Cd Antigen Cd16b protein FCGR3B protein CD16B protein FCG3 protein FCGR3 protein IGFR3 protein

Information sourced from Uniprot.org