||Human, Mouse, Rat
||FOR RESEARCH USE ONLY (RUO).
||Rabbit polyclonal antibody Anti-Ubiquitin carboxyl-terminal hydrolase isozyme L1 is suitable for use in Western Blot and Immunohistochemistry.
||Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
||The antibody was affinity-purified from rabbit serum by affinity-chromatography using a specific immunogen.
||IHC-p 1:50-200, WB 1:500-2000
||Store at-20°C, and avoid repeat freeze-thaw cycles.
||This antibody detects endogenous levels of human PGP9.5
||Recombinant Protein derived from human PGP9.5
| Post Translational Modifications || O-glycosylated. |
| Function || Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (Probable). This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. |
| Protein Name || Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1Uch-L1Neuron Cytoplasmic Protein 9.5Pgp 9.5Pgp9.5Ubiquitin Thioesterase L1 |
| Database Links || Reactome: R-HSA-5689603 |
| Cellular Localisation || CytoplasmEndoplasmic Reticulum MembraneLipid-AnchorAbout 30% Of Total Uchl1 Is Associated With Membranes In Brain |
| Alternative Antibody Names || Anti-Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 antibodyAnti-Uch-L1 antibodyAnti-Neuron Cytoplasmic Protein 9.5 antibodyAnti-Pgp 9.5 antibodyAnti-Pgp9.5 antibodyAnti-Ubiquitin Thioesterase L1 antibodyAnti-UCHL1 antibody |
Information sourced from Uniprot.org
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